By Joel Havemann
"I'm flat on my again on a sofa that is too brief in a windowless room within the bureau. i will not even sit down at a working laptop or computer, less make a keyboard paintings. My legs and arms are shaking uncontrollably. even if i'm purely fifty three years previous, i've got already been being affected by Parkinson's sickness for seven years. And immediately the affliction is winning." So starts off Joel Havemann's account of the insidious disorder that's Parkinson's. Into his personal tale, Havemann weaves available reasons of the way Parkinson's disrupts the brain's circuitry, how signs are controlled via medications and surgical procedure, and the way humans take care of the disease's mental demanding situations. The paperback version brings the dialogue of treatments and study completely modern.
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Extra resources for A Life Shaken: My Encounter with Parkinson's Disease
On any given trip, the chances are about four out of ﬁve that a dopamine molecule will evade its predators and make it back to its home nerve cell safely. But that means each dopamine molecule has scarcely more than a 50-50 chance of surviving three plunges into the synapse. Only about one molecule in ten is likely Image not available. 3. A, When a command (such as ‘‘run’’) originates in the cerebral cortex (the thinking part of the brain), it triggers a cascade of electrical signals, some of which pass through the substantia nigra before looping back to the motor area of the cortex and ﬁnally traveling to the body—in this case, the legs.
She instructed me to push back on the arms of the lounge chair until the back tilted backward and the bottom part of the front of the chair converted into a footrest—only for my long legs it was more like a calf-rest, with my feet dangling uncomfortably o√ the end. The tone machine started making very-high-frequency sounds. ‘‘Just lie back comfortably and close your eyes,’’ she said quietly. ’’ Sure enough, the chimes from the tone machine came down in pitch. ‘‘You can feel the pressure ﬂowing out of your scalp and your forehead.
The two medications, which fool the brain into thinking they are a chemical that is in short supply in Parkinson’s disease, promised little more than a modest improvement over two drugs that had been on the market for years. Still being tested, however, were much more futuristic treatments aimed at either repairing or replacing the cells that have fallen victim to the disease. Researchers are trying to develop a reliable system for delivering chemicals called growth factors to the brain, where they hold out the prospect of restoring diseased brain cells to health.
A Life Shaken: My Encounter with Parkinson's Disease by Joel Havemann